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Mark Dore, Editor in Chief
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NEWS
INDIANA CONTINUED
“Around 20 states have religious
freedom restoration acts or similarities
that mirror or try to resemble what was
passed in 1993,” Penrose said. “The rea
son the states have to pass these laws is
the Supreme Court actually issued opin
ion in 1997 in a case. City of Boerne v.
Flores, that told congress they can’t issue
a RFRA for the states.”
Texas is one of the states that passed
an RFRA in 1999, but Penrose said the
Texas law is not as expansive as the In
diana law.
Penrose said the growing number of
RFRAs are a reaction to fears that the
Supreme Court will constitutionalize
same-sex marriage as well as a reaction
to local non-discrimination laws cur
rently in place.
“Some states and some cities have
non-discrimination clauses that they
passed at the most local level of legis-
ZHU CONTINUED
et cetera. These characteristics
can be used as the local stimuli
for the purposes of drug
delivery and therapy. The matrix
metalloproteinase 2, MMP2, a
major enzyme in the cancer tissue,
is one of them. In my lab, we have
designed various nano-sized drug
carriers which could respond to
the tumoral MMP2 and specifically
deliver toxic drugs to cancer cells.
By this way, the drugs will stay
with the nanocarriers without drug
"leakage," and then be released
from the nanocarriers once
entering the cancer cells.
THE BATTALION: What progress
has your team made with this
targeted cancer treatment?
ZHU: So far, we have successfully
prepared several MMP2-sensitive
nanomaterials which could be
used to construct cancer-specific
drug delivery systems. They
have been preliminarily tested in
various human cancer cell lines
and tumor-bearing mice. In these
models, they showed better
anticancer effects and less toxicity
to normal tissues, compared to
the chemotherapy drug alone.
However, more studies are needed
before they can go to clinical trial.
lation, saying you cannot discriminate
in public accommodations against indi
viduals based on sexual orientation, or
variety of other classes,” Penrose said.
“These religious freedom restoration
acts then serve as a defense to that.”
Saad Dawoodi, biochemistry senior
and president of Shades of Queer, an
LGBT student organization, said this
law represents a recent trend toward
“right to discriminate” legislation, and
that it’s an example of how religion is
“weaponized” to combat the legal gains
of the LGBT community.
“The right to discriminate legislation
has been on the rise recently,” Dawoodi
said. “I’m not surprised in the least, and
this backlash against the LGBT rights
movement and community is obviously
because people who are not in favor of
the LGBT community or movement are
scared that essentially that they’re going
to lose their toys.”
Brandon Orr, graduate student and
president of the campus Association of
PROVIDED
Lin Zhu, assistant professor of
pharmaceutical sciences, works
with developing nanotechnology to
improve cancer treatments
THE BATTALION: What
adverse side effects could your
research prevent patients from
experiencing?
ZHU; The major cause of the side
effects of the chemotherapy drugs
is their toxicity to the healthy cells
[and] tissues. The drug-related
toxicity [and] side effects, which
are very common in the patients
receiving thermotherapy, include
the fatigue, hair loss, blood
disorders, nausea and vomiting,
et cetera. These side effects can
2
Baptist Students, said although gay mar
riage is against his beliefs, he doesn’t
believe that merits a discriminatory at
titude toward same-sex couples.
“I definitely don’t think that they
should be able to just turn anyone away
because of what they’re affiliated with,
I think that’s kind of dumb,” Orr said.
“The Bible is very specific about gay
marriage and it’s wrong, and I believe
that it’s wrong, but if someone was gay
and they came into my store, there’s no
way I would just turn them away.”
Dawoodi said the media coverage,
controversy and protest that came as a
result of this legislation is representative
of the power of the people.
“I think it sends a message to corpo
rations that have gotten a lot of power
over the past decades,” Dawoodi said. “I
think it’s a good reminder for companies
and America as a whole that the com
munity can mobilize.”
be most likely minimized by our
strategies.
THE BATTALION: Are there any
possible drawbacks to this new
type of treatment?
ZHU; I have to say that nothing is
perfect, including our anti-cancer
strategy. However, to the best
of our knowledge, our strategy
is superior to the currently used
anticancer strategies in terms of
the cancer specificity, anti-cancer
efficacy and side effects. Since the
studies in my lab are preclinical
studies, a lot of tests have to be
done to confirm its efficacy as well
as assess its possible side effects
before it can really benefit cancer
patients.
THE BATTALION: What are the
implications for your research
on the fields of pharmacy and
medicine?
ZHU: Our research is driven by the
need to improve the formulations
and drug delivery systems of
current chemotherapy drugs and
to develop a strategy that can be
a stepping stone towards attaining
the ultimate goal of cancer-
specific drug delivery and therapy.
I hope that our work could be a
paradigm of both the anti-cancer
drug development and the cancer-
specific chemotherapy.
II I,. J 8
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What's your
BIG IDEA?
THE RAYMOND
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