4B
Thursday, March 7, 2002
THE BA’
Doctors transplant human uter
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LONDON (AP) — Doctors in Saudi
Arabia have performed the first human
uterus transplant, which produced two
menstrual periods before it failed and had
to be removed.
The experiment indicated a womb trans
plant is technically achievable, but experts say
it is highly risky and ethically questionable.
Some say it will not be practical until less
toxic anti-rejection drugs become available.
The idea of uterus transplants was first
explored in the 1950s. But after 20 years of
failed experiments on dogs and baboons,
many scientists considered it impossible
because of the complex blood vessels that
must be connected and because of fears that
anti-rejection drugs could harm a fetus.
Dr. Wafa Fageeh, a professor at Abdulaziz
University who performed the transplant
with her team at King Fahad Hospital and
Research Center in Jiddah, Saudi Arabia,
called the operation “a good start.”
“It is technically feasible, theoretically
desirable, but presently unsafe,” said
Roger Gosden, a fertility pioneer at
Eastern Virginia Medical School in
Norfolk, Va. “Their results reveal the risks
and this procedure awaits the development
of safe immunosuppression.
“A transplant to save life is an acceptable
risk, but not one for fertility, when there are
alternatives " he said. “This is why we would
never be given ethical clearance to try this in
the United States” for the foreseeable future.
The operation, reported this week in the
International Journal of Gynecology and
Obstetrics, failed because a blood vessel
a
They took a concept that
everyone thought was
undoable and they did it.
Dr. Louis Keith
obstetrician
the uterus to survive 99 daysajvj
a uterus is supposed to tuncfe j
to menstruate,” said Keith, y j
editor of the journal that publisi
The transplant, using the\
year-old post-menopausal wo
to have a hysterectomy, [
April 6, 2(X)0, on a 26-yeJ
woman w ho had lost her uter.
excessive bleeding after childrl
The recipient was given -i
pills, but nine days after the 1
body rejected the womb. Hou : |
were able to control it withdrj
Hormone treatment wasgivj
the womb’s lining and it grt.l
limeters thick, indicating tkj
were getting through andthai:|
w as good, the researchers rep |
Menstrual periods happen 5
supplying the uterus developed a clot,
which cut off the blood supply.
“You have to give them credit. They took
a concept that everybody thought was
undoable and they did it," said Dr. Louis
Keith, an obstetrician and gynecologist at
Northwestern Memorial Hospital in Chicago
who was not involved in the research.
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mg of
reaches
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he womb, prompted b
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NEWS IN BRIEF
George Washington letter found in N.Y.
ORANGE, Va. (AP) — A letter written by George Washington
in 1788 and stolen from a home in Virginia has been found in
New York City.
The letter, valued at $500,000, had been sold to a collector in
New York for far less than its value, authorities said Tuesday. It
was to be retrieved Thursday by Orange County sheriff's officials.
Thomas Paytes, 35, of Orange County, was charged with
grand larceny in the Feb. 25 theft. Paytes worked fc”
of the letter and had access to his home, the sbe^'
ment said. He was arrested in Washington duringth
Orange County Sheriff C.G. Feldman would not :
letter's owner.
The letter was written to Washington's person
Tobias Lear, nine months before Washington became
In it, Washington discusses Virginia's ratification of
Constitution, which had taken place three days earlier:
an agreemc
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OUT MOTteS STUDLNT
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