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Mice genes studied to cure disease
THE BATTALION Page 5
WEDNESDAY, NOVEMBER 29, 1978
By BECKY DOBSON
Battalion Reporter
The best laid schemes of mice and
men gang aft agley (go off the
planned line). —Robert Burns
Present research by a geneticist at
Texas A&M University continues to
validate Burns’s earlier observation
of the similarities between mice and
men.
Dr. Jim Womack is studying
genes which cause birth defects in
mice to gain insight into the cause
and possible cure of birth defects in
humams. The project is one of vari
ous studies being conducted by the
Institute of Comparative Medicine
jointly administered by Texas A&M
and Baylor College of Medicine at
Houston.
“We are comparing animal
functions and disease with the dis
eases of human beings,” says Dr.
William McCulloch, director of the
Navajo Police
arrest protestor
United Press International
WINDOW ROCK, Ariz. — Navajo Tribal Police Tuesday used
clubs to clear a park where a group of Indians had set up camp
Monday in a protest of tribal officials and policies.
Initial reports said at least 15 persons were arrested, including the
leader of the occupation, Larry Anderson.
Witnesses said at least one protestor suffered a head injury during
the arrests.
Navajo Police could not be reached for comment. Sources in Win
dow Rock said the police had turned off the telephone switchboard
for all Navajo Tribal offices.
The clash between police and an estimated 50 protestors appar
ently began after the protestors rejected a request by tribal officials to
move to the Tse Bonito Park, just a few miles east of Window Rock in
New Mexico.
Witnesses said Navajo Police then sealed off entrances to the park.
The witnesses said a group of elderly Navajo women then approached
the officers and began taunting them. After about 10 minutes, an
officer gave a command for the officers to move forward. The women
began resisting but the officers continued their march. At that point,
witnesses said several younger men charged the police. The officers
began using billy clubs to subdue the men and began arresting them.
Witnesses said persons remaining in the park scattered.
Sources said charges against those arrested had not been specified.
They were not expected to be arraigned until today.
The group calling itself the Dine Bii Coalition moved into the park
Monday in an apparent continuation of a protest that began with the
brief occupation of the tribal headquarters building the day before
the Nov. 14 tribal elections. Anderson also led that takeover.
The protestors, originally estimated at about 125 persons, said they
would remain in the park until their demands’ were met.
However, Katherine Ott, a member of the tribal legal staff, said the
protestors’ demands were not clear. She said the group was preparing
earlier Tuesday to send a delegation to meet with tribal officials to
discuss their demands.
Tribal officials had urged the protestors to move to the other park
because of better sanitary conditions, because of the danger of falling
rock and because Window Rock park was “a sacred area.”
Anderson said the occupation would not be violent and said none of
the protesters carried firearms. He said the demonstrators had
enough food to last for two years and said they would be joined by
others later.
He said the group’s demands included the elimination of the
Navajo Supreme Judicial Council and more responsive tribal officials.
Anderson and six other men occupied the headquaters building
Nov. 13 for about four hours in a protest against the candidates for
tribal office. They surendered peacefully and were held on several
federal charges that later were dismissed. The incident still is under
investigation.
institute. “Many of the diseases that
animals have are similar to those in
people. Since we obviously cannot
experiment on people, we are able
to study the natural diseases of ani
mals. By finding the cure and the
reasons for their diseases we can
also gain insight into the solutions of
similar diseases in man.”
Womack’s study involves genetic
mutations in mice which cause lipid
storage diseases. The diseases affect
muscle and nerve control. Children
suffering from some of the most se
rious of the diseases live only two to
three years, Womack says.
“Many diseases in humans have
not been solved because we don’t
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understand the activities of a normal
cell,” Womack says. His work is
aimed at studying the normal pro
cesses of the cell, which will aid him
in determining exactly what goes
wrong in genetic production that
causes cell disorders and disease.
The basic problem is lipid storage
diseases, Womack says, is the fail
ure of cell enzymes to be made and
processed in the cells of individuals.
“One of the most significant dis-
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coveries made so far has been that
there are more than one class of
genes involved in these diseases —
the genes that regulate the amount
of enzyme produced and the genes
responsible for packaging the
enzymes. Our future work will be
directed toward a better under
standing of how the genes can be
controlled harmoniously.”
Womack says laboratory mice
make good models for studying the
genetics of enzyme processing. He
says mice are so inbred that they
may be treated as genetic copies of
one another. This condition is not
common in other animals.
The National Foundation-March
of Dimes has contributed $26,000 to
Womack’s research on birth defects.
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